Cranial Cavernous Malformations

Cavernous malformations.

Cavernous malformations (CMs) are vascular lesions found in the central nervous system (CNS) and throughout the body and have been called cavernomas, cavernous angiomas, and cavernous hemangiomas. This article discusses the epidemiology, natural history, diagnosis, treatment and follow-up of children who are found to harbor these lesions. CMs affect children by causing hemorrhage, seizure, foca...

Pathology of cavernous malformations

Cerebrovascular malformations are classified as cavernous malformations (CMs), arteriovenous malformations (AVMs), developmental venous anomalies (DVAs) and capillary telangiectasias (CTs). CMs are the second most common form of cerebrovascular malformation and constitute up to 10–15% of the total [1,2]. In the past, CMs were not visualized on radiological examinations such as CT scanning or an...

Radiosurgery for cavernous malformations.

The role of radiosurgery for cavernous malformations of the brain remains to be fully defined. We have used Gamma Knife radiosurgery for selected patients with symptomatic, hemorrhagic malformations in high-risk brain locations. Indications, techniques, and results are presented.

Cerebral cavernous malformations.

Cavernous malformations of the brainstem.

In 1966, McCormick categorized nonneoplastic vascular malformations of the central nervous system into four types: arteriovenous malformations, venous angiomas, capillary telangiectasias, and cavernous malformations (CM).23 In the 4 decades since this original classification, significant work has been done to characterize the epidemiology, pathogenesis, natural history, proper management, and p...